SCHEMBL7572975

SCHEMBL7572975

O[C]1CCCCC1C1CCCCCCC1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
ALOX12 P18054 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NOS1 P29475 2/20 0.32
NOS2 P35228 2/20 0.32
NOS3 P29474 1/20 0.32
SLC18A3 Q16572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10426014 1.00 ALDH1A1 (0.38) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL4064825 0.92 ALDH1A1 (0.35) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL3371097 0.71
SCHEMBL3477839 0.70 KMT2A (0.50) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL7706359 0.70 KMT2A (0.50) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL3721835 0.70 KMT2A (0.50) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL7139457 0.70 KMT2A (0.50) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL18752554 0.70 ALDH1A1 (0.34) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL3397908 0.70 KMT2A (0.50) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL18753267 0.70 ALDH1A1 (0.34) ALDH1A1KMT2AMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0676201-B1 Use of a riminophenazine for treating MDR resistance UNIV PRETORIA (ZA) 2002-09-11 EP disclosed
EP-0676201-A2 Use of a riminophenazine for treating MDR resistance ADCOCK INGRAM LIMITED (ZA) 1995-10-11 EP disclosed