Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CCR2 | P41597 | 1/20 | 0.58 |
| ▸ | ACLY | P53396 | 1/20 | 0.58 |
| ▸ | CLK1 | P49759 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592771 | 0.89 | MEN1 (0.74) | SLC40A1MEN1KMT2AGAANR3C1 | |
| SCHEMBL7572582 | 0.87 | CLK1 (0.67) | SLC40A1MEN1KMT2AGAANR3C1 | |
| SCHEMBL7594309 | 0.86 | KMT2A (0.63) | SLC40A1MEN1KMT2AGAANR3C1 | |
| SCHEMBL7591899 | 0.85 | KMT2A (0.61) | SLC40A1MEN1KMT2AGAANR3C1 | |
| SCHEMBL7598878 | 0.84 | PTGES2 (0.62) | SLC40A1MEN1KMT2AGAAAR | |
| SCHEMBL7572596 | 0.84 | MEN1 (0.67) | SLC40A1MEN1KMT2AGAANR3C1 | |
| SCHEMBL10143421 | 0.82 | MEN1 (0.66) | SLC40A1MEN1KMT2AGAANR3C1 | |
| SCHEMBL10622385 | 0.82 | MEN1 (0.66) | SLC40A1MEN1KMT2AGAANR3C1 | |
| SCHEMBL3762909 | 0.81 | PGR (0.77) | MEN1KMT2AGAANR3C1PGR | |
| SCHEMBL7568254 | 0.81 | MEN1 (0.57) | SLC40A1MEN1KMT2AGAANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083629-A1 | BISSULFONAMIDE DERIVATIVES AS INHIBITORS OF DEHYDROQUINATE SYNTHETASES AND TYPE II DEHYDROQUINASES | ARROW THERAPEUTICS LIMITED (GB) | 2002-10-24 | — | — | WO | disclosed |