Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.58 |
| ▸ | ACE | P12821 | 11/20 | 0.58 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 4/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.41 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573257 | 1.00 | MME (0.58) | MMEACECTSBITGB3ITGAV | |
| SCHEMBL8446420 | 0.94 | MME (0.50) | MMEACECTSBITGB3ITGAV | |
| SCHEMBL7572261 | 0.89 | MME (0.66) | MMEACECTSBITGB3ITGAV | |
| SCHEMBL7572256 | 0.89 | MME (0.66) | MMEACECTSBITGB3ITGAV | |
| SCHEMBL8446421 | 0.88 | MME (0.43) | MMEACECTSB | |
| SCHEMBL7567275 | 0.88 | MME (0.62) | MMEACECPA1ACE2 | |
| SCHEMBL7567282 | 0.88 | MME (0.62) | MMEACECPA1ACE2 | |
| SCHEMBL8027176 | 0.88 | MME (0.73) | MMEACECPA1ACE2 | |
| SCHEMBL7570155 | 0.86 | MME (0.70) | MMEACECTSBCPA1ACE2 | |
| SCHEMBL7567672 | 0.85 | MME (0.61) | MMEACEITGB3ITGAVCPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |