Urethane

Urethane

SCHEMBL7573316

C=C.C=C.CCOC(N)=O

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.88
ALDH1A1 P00352 5/20 0.50
LMNA P02545 4/20 0.48
HSD17B10 Q99714 2/20 0.48
GAA P10253 3/20 0.46
MGAM O43451 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
SOAT1 P35610 1/20 0.46
CHRM2 P08172 2/20 0.42
CHRM4 P08173 2/20 0.42
CHRM5 P08912 2/20 0.42
CHRM1 P11229 2/20 0.42
CHRM3 P20309 2/20 0.42
TSHR P16473 2/20 0.42
CHRNB2 P17787 2/20 0.42
CHRNA4 P43681 2/20 0.42
HTR1A P08908 1/20 0.42
CYP2C19 P33261 1/20 0.42
CHRNA7 P36544 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL1684893 1.00
Urethane SCHEMBL28197447 0.94
Urethane SCHEMBL3735741 0.94
Urethane SCHEMBL8136 0.94
Urethane SCHEMBL27632514 0.94 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL367439 0.94 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL8129017 0.94 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL8505249 0.94 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL8830978 0.94 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL11589533 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4238914-A Resiliently cushioned adhesive-applied rebound wall surfacing system and method of construction VERSAWOOD FLOORS INC CHANGED TO AMERICAN SPORTSURFACING CO INC 1980-12-16 US claimed
EP-0854024-B1 Thin-film fabrication method and apparatus NAT INST OF ADVANCED IND SCIEN (JP) 2002-09-18 EP disclosed
US-6319321-B1 Thin-film fabrication method and apparatus AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) 2001-11-20 US disclosed
EP-0854024-A2 Thin-film fabrication method and apparatus Agency of Industrial Science and Technology of Ministry of International Trade and Industry (JP) 1998-07-22 EP disclosed
US-4439585-A Polyurethane diacrylate compositions as carrier for pharmacological agents TYNDALE PLAINS-HUNTER, LTD. (US) 1984-03-27 US disclosed
US-4439584-A Gas and ion permeable membranes formed of polyurethane diacrylate compositions TYNDALE PLAINS-HUNTER, LTD. (US) 1984-03-27 US disclosed
US-4439583-A Polyurethane diacrylate compositions useful in forming canulae TYNDALE PLAINS-HUNTER, LTD. (US) 1984-03-27 US disclosed
US-4424305-A Surgical implants formed of polyurethane diacrylate compositions TYNDALE PLAINS-HUNTER, LTD. (US) 1984-01-03 US disclosed
US-4408023-A HYDROPHILIC, RESILIENT TYNDALE PLAINS-HUNTER, LTD. (US) 1983-10-04 US disclosed
US-4359558-A REACTING A POLYURETHANE WITH AN ETHER ESTER OF ACRYLIC OR METHACRYLIC ACID TYNDALE PLAINS-HUNTER, LTD. (US) 1982-11-16 US disclosed