SCHEMBL7573482

SCHEMBL7573482

O=S(=O)(Nc1cccc(Cl)c1O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERBB2 P04626 1/20 0.60
HSP90AA1 P07900 1/20 0.60
HSP90AB1 P08238 1/20 0.60
GAA P10253 6/20 0.60
ALDH1A1 P00352 4/20 0.60
ALOX15 P16050 3/20 0.60
HSD17B10 Q99714 3/20 0.60
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
HPGD P15428 1/20 0.60
TSHR P16473 3/20 0.58
KDM4E B2RXH2 1/20 0.58
PTK2B Q14289 1/20 0.58
RECQL P46063 2/20 0.54
HTT P42858 3/20 0.52
PKM P14618 1/20 0.52
SLC40A1 Q9NP59 1/20 0.52
ALOX12 P18054 3/20 0.52
MAPT P10636 1/20 0.51
MAPK1 P28482 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6801689 0.88 RECQL (0.62) ERBB2HSP90AA1HSP90AB1GAAALDH1A1
SCHEMBL3791578 0.84 TSHR (0.74) ERBB2HSP90AA1HSP90AB1GAAALDH1A1
SCHEMBL11785781 0.83 EP300 (0.60) ERBB2HSP90AA1HSP90AB1GAAALDH1A1
SCHEMBL7569069 0.83 TSHR (0.58) ERBB2HSP90AA1HSP90AB1GAAALDH1A1
SCHEMBL6565566 0.82 CA12 (0.55) GAAALDH1A1MEN1KMT2AHPGD
SCHEMBL1151730 0.82 ERBB2 (0.59) ERBB2HSP90AA1HSP90AB1GAAALDH1A1
SCHEMBL5694590 0.82 ERBB2 (0.59) ERBB2HSP90AA1HSP90AB1GAAALDH1A1
SCHEMBL3791864 0.81 TSHR (0.57) ERBB2HSP90AA1HSP90AB1GAAALDH1A1
SCHEMBL3785727 0.80 RECQL (0.62) ERBB2HSP90AA1HSP90AB1GAAALDH1A1
SCHEMBL8981191 0.80 ERBB2 (0.60) ERBB2HSP90AA1HSP90AB1GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed