SCHEMBL6801689

SCHEMBL6801689

O=S(=O)(Nc1cccc(NS(=O)(=O)c2ccccc2)c1O)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 2/20 0.62
GAA P10253 5/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
HTT P42858 2/20 0.59
MAPT P10636 2/20 0.59
MAPK1 P28482 1/20 0.59
ALDH1A1 P00352 4/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
GFER P55789 1/20 0.57
APOBEC3G Q9HC16 1/20 0.57
MMP2 P08253 1/20 0.56
ERBB2 P04626 1/20 0.56
HSP90AA1 P07900 1/20 0.56
HSP90AB1 P08238 1/20 0.56
ALOX15 P16050 2/20 0.55
HSD17B10 Q99714 2/20 0.55
HPGD P15428 1/20 0.55
IL1RN P18510 1/20 0.55
KEAP1 Q14145 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7573482 0.88 ERBB2 (0.60) RECQLGAAMEN1KMT2AHTT
SCHEMBL28637555 0.86 KMT2A (0.58) RECQLGAAMEN1KMT2AHTT
SCHEMBL2067538 0.85 ALDH1A1 (0.68) RECQLGAAMEN1KMT2AHTT
SCHEMBL752345 0.84 GAA (0.80) RECQLGAAMEN1KMT2AHTT
SCHEMBL17978559 0.82 MAPT (0.58) RECQLGAAMEN1KMT2AHTT
SCHEMBL7570770 0.82 GAA (0.61) RECQLGAAMEN1KMT2AHTT
SCHEMBL8981191 0.80 ERBB2 (0.60) RECQLGAAMEN1KMT2AHTT
SCHEMBL8016513 0.80 GAA (0.59) RECQLGAAMEN1KMT2AHTT
SCHEMBL10409886 0.80 RECQL (0.68) RECQLGAAMEN1KMT2AHTT
SCHEMBL3785727 0.80 RECQL (0.62) RECQLGAAMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed