Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573662 | 1.00 | REN (0.53) | REN | |
| SCHEMBL7565724 | 0.92 | REN (0.55) | REN | |
| SCHEMBL7565713 | 0.92 | REN (0.55) | REN | |
| SCHEMBL7635268 | 0.90 | REN (0.48) | REN | |
| SCHEMBL7635277 | 0.89 | REN (0.54) | REN | |
| SCHEMBL7632877 | 0.89 | REN (0.49) | REN | |
| SCHEMBL9727990 | 0.89 | REN (0.54) | REN | |
| Hydrochloric Acid SCHEMBL9728017 | 0.89 | REN (0.48) | REN | |
| SCHEMBL7632889 | 0.89 | REN (0.49) | REN | |
| Hydrochloric Acid SCHEMBL9728008 | 0.89 | REN (0.48) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140011-A | Hypotensive agents | HOFFMANN-LA ROCHE, INC. (US) | 1992-08-18 | — | — | US | disclosed |
| EP-0391179-A2 | Peptide derivatives of amino acids having a renin-inhibiting effect | F. HOFFMANN-LA ROCHE AG (CH) | 1990-10-10 | — | — | EP | disclosed |