Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7571354 | 1.00 | PARP10 (0.30) | PARP10PARP11KDM4EMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL7572716 | 0.99 | PARP10 (0.31) | PARP10PARP11 | |
| Hydrochloric Acid SCHEMBL7573631 | 0.94 | PARP10 (0.32) | PARP10PARP11 | |
| Hydrochloric Acid SCHEMBL5083942 | 0.91 | KDM4E (0.33) | KDM4EMEN1NPC1USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5084162 | 0.91 | KDM4E (0.33) | KDM4EMEN1NPC1USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5083597 | 0.89 | CAMK2A (0.31) | KDM4EMEN1NPC1USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5084187 | 0.88 | CAMK2A (0.32) | KDM4EMEN1NPC1USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5080622 | 0.84 | KDM4E (0.32) | KDM4EMEN1NPC1USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL649398 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL401171 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019504-A1 | Stereospecific; low molecular weight | MITSUI CHEMICALS, INC. (JP) | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019504-A1 | Stereospecific; low molecular weight | RPLP1, RPS4Y1, POLA1 | PARP10 904/4885PARP11 215/4885KDM4E 2167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.