Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575072 | 0.93 | NAMPT (0.33) | PDE2ADHODHMAPK1NAMPTEPHX2 | |
| SCHEMBL7575471 | 0.88 | DHODH (0.33) | PDE2ADHODHMAPK1NAMPTEPHX2 | |
| SCHEMBL7576396 | 0.86 | DHODH (0.31) | DHODH | |
| SCHEMBL27287091 | 0.85 | DHODH (0.34) | PDE2ADHODHNAMPTEPHX2 | |
| SCHEMBL27298864 | 0.84 | DHODH (0.32) | PDE2ADHODHNAMPTEPHX2 | |
| SCHEMBL7573406 | 0.84 | PDE2A (0.33) | PDE2ADHODH | |
| SCHEMBL7573404 | 0.84 | PDE2A (0.33) | PDE2ADHODH | |
| SCHEMBL7574312 | 0.81 | DHODH (0.32) | PDE2ADHODHMAPK1EPHX2 | |
| SCHEMBL7574237 | 0.81 | DHODH (0.33) | PDE2ADHODHMAPK1 | |
| SCHEMBL7575613 | 0.81 | DHODH (0.33) | PDE2ADHODHMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | claimed |
| CN-1039229-C | Herbicides | PHONE POULENC AGRICULTURE LTD (GB) | 1998-07-22 | — | — | CN | claimed |
| CN-1091739-A | Weedicide | PHONE POULENC AGRICULTURE LIMI (GB) | 1994-09-07 | — | — | CN | claimed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | claimed |
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| CN-1039229-C | Herbicides | PHONE POULENC AGRICULTURE LTD (GB) | 1998-07-22 | — | — | CN | disclosed |
| US-5374606-A | Pre- and postemergence | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |