SCHEMBL7576396

SCHEMBL7576396

C=CC[S+]([O-])Cc1cc(Br)ccc1C(=O)c1cnoc1C1CC1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7575072 0.87 NAMPT (0.33) DHODH
SCHEMBL7573673 0.86 PDE2A (0.32) DHODH
SCHEMBL7575471 0.84 DHODH (0.33) DHODH
SCHEMBL27298864 0.82 DHODH (0.32) DHODH
SCHEMBL7573406 0.82 PDE2A (0.33) DHODH
SCHEMBL7573404 0.82 PDE2A (0.33) DHODH
SCHEMBL27287091 0.82 DHODH (0.34) DHODH
SCHEMBL7576297 0.81 DHODH (0.31) DHODH
SCHEMBL7573690 0.80 DHODH (0.31) DHODH
SCHEMBL27379398 0.78 DHODH (0.34) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609798-B1 4-Benzoyl isoxazoles and their use as herbicides AVENTIS AGRICULTURE LTD (GB) 2002-10-02 EP claimed
CN-1039229-C Herbicides PHONE POULENC AGRICULTURE LTD (GB) 1998-07-22 CN claimed
EP-0609798-A1 4-Benzoyl isoxazoles and their use as herbicides RHONE POULENC AGRICULTURE LTD. (GB) 1994-08-10 EP claimed
EP-0609798-B1 4-Benzoyl isoxazoles and their use as herbicides AVENTIS AGRICULTURE LTD (GB) 2002-10-02 EP disclosed
CN-1039229-C Herbicides PHONE POULENC AGRICULTURE LTD (GB) 1998-07-22 CN disclosed
US-5374606-A Pre- and postemergence RHONE-POULENC AGRICULTURE LIMITED (GB) 1994-12-20 US disclosed
EP-0609798-A1 4-Benzoyl isoxazoles and their use as herbicides RHONE POULENC AGRICULTURE LTD. (GB) 1994-08-10 EP disclosed