Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.71 |
| ▸ | ACE | P12821 | 13/20 | 0.71 |
| ▸ | CPA1 | P15085 | 2/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | FCER2 | P06734 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573682 | 1.00 | MME (0.71) | MMEACECPA1ACE2CA2 | |
| SCHEMBL7569444 | 0.93 | MME (0.74) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL7567514 | 0.93 | MME (0.74) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL7569434 | 0.93 | MME (0.74) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL8447138 | 0.90 | MME (0.58) | MMEACEFCER2 | |
| SCHEMBL7569404 | 0.90 | MME (0.69) | MMEACECPA1ACE2FCER2 | |
| SCHEMBL7572307 | 0.90 | MME (0.69) | MMEACECPA1ACE2FCER2 | |
| SCHEMBL7569054 | 0.89 | MME (0.67) | MMEACECPA1ACE2 | |
| SCHEMBL7569057 | 0.89 | MME (0.67) | MMEACECPA1ACE2 | |
| SCHEMBL7575443 | 0.88 | MME (0.67) | MMEACECPA1ACE2PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |