Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.58 |
| ▸ | ACE | P12821 | 9/20 | 0.58 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446481 | 0.93 | MME (0.62) | MMEACETACR1CTSLCTSB | |
| SCHEMBL8451262 | 0.90 | MME (0.54) | MMEACETACR1CTSBPOLB | |
| SCHEMBL7573678 | 0.90 | MME (0.71) | MMEACEFCER2 | |
| SCHEMBL7573682 | 0.90 | MME (0.71) | MMEACEFCER2 | |
| SCHEMBL8446463 | 0.89 | MME (0.55) | MMEACETACR1CTSLCTSB | |
| SCHEMBL8449480 | 0.89 | MME (0.53) | MMEACETACR1CTSLCTSB | |
| SCHEMBL27489674 | 0.89 | MME (0.68) | MMEACETACR1CTSLCTSB | |
| SCHEMBL8450109 | 0.87 | MME (0.52) | MMEACETACR1CTSLCTSB | |
| SCHEMBL8447131 | 0.86 | MME (0.52) | MMEACETACR1CTSLCTSB | |
| SCHEMBL27441340 | 0.86 | MME (0.69) | MMEACETACR1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |