SCHEMBL757371

SCHEMBL757371

CCCCOCC(O)CN(CCO)CCO

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.53
ALDH1A1 P00352 3/20 0.51
HTT P42858 2/20 0.47
TSHR P16473 1/20 0.45
KDM4E B2RXH2 2/20 0.44
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 2/20 0.43
LPAR5 Q9H1C0 1/20 0.41
GAA P10253 2/20 0.41
NPSR1 Q6W5P4 1/20 0.40
SPHK1 Q9NYA1 1/20 0.40
HSD17B10 Q99714 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ALOX15 P16050 1/20 0.38
NCOA3 Q9Y6Q9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2987001 0.93 USP2 (0.64) USP2ALDH1A1HTTKDM4EMAPK1
SCHEMBL728005 0.93 USP2 (0.64) USP2ALDH1A1HTTKDM4EMAPK1
SCHEMBL2995939 0.93 USP2 (0.64) USP2ALDH1A1HTTKDM4EMAPK1
SCHEMBL2991718 0.93 USP2 (0.64) USP2ALDH1A1HTTKDM4EMAPK1
SCHEMBL728014 0.93 USP2 (0.64) USP2ALDH1A1HTTKDM4EMAPK1
SCHEMBL18296270 0.91 ALDH1A1 (0.55) USP2ALDH1A1HTTTSHRKDM4E
SCHEMBL26942167 0.90 USP2 (0.60) USP2ALDH1A1HTTKDM4EMAPK1
SCHEMBL13488462 0.89 USP2 (0.52) USP2ALDH1A1HTTTSHRKDM4E
SCHEMBL13609390 0.89 USP2 (0.52) USP2ALDH1A1HTTTSHRKDM4E
SCHEMBL14278855 0.88 ALDH1A1 (0.42) USP2ALDH1A1HTTTSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10829718-B2 Detergent composition comprising a carbinol functional trisiloxane DOW SILICONES CORPORATION (US) 2020-11-10 US disclosed
US-20190112549-A1 DETERGENT COMPOSITION COMPRISING A CARBINOL FUNCTIONAL TRISILOXANE DOW SILICONES CORPORATION 2019-04-18 US disclosed
WO-2017189703-A1 DETERGENT COMPOSITION COMPRISING A CARBINOL FUNCTIONAL TRISILOXANE DOW CORNING CORPORATION (US) 2017-11-02 WO disclosed
EP-1618146-B9 STABILISER SYSTEM FOR THE STABILISATION OF HALOGENATED POLYMERS GALATA CHEMICALS GMBH (DE) 2012-03-21 EP disclosed
EP-1618146-B1 STABILISER SYSTEM FOR THE STABILISATION OF HALOGENATED POLYMERS GALATA CHEMICALS GMBH (DE) 2011-08-17 EP disclosed
EP-1461375-B1 PRESTABILIZATION OF HALOGEN-CONTAINING POLYMERS CHEMTURA VINYL ADDITIVES GMBH (DE) 2010-01-27 EP disclosed
US-7622541-B2 Polyurethane coating THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2009-11-24 US disclosed
US-7615604-B2 Diols formed by ring-opening of epoxies THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2009-11-10 US disclosed
US-7612133-B2 Prestabilization of halogen-containing polymers CHEMTURA VINYL ADDITIVES GMBH (DE) 2009-11-03 US disclosed
US-7432399-B2 Diols formed by ring-opening of epoxies THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-10-07 US disclosed
EP-1645592-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers Rohm and Haas Company (US) 2006-04-12 EP disclosed
US-20060052497-A1 Stabilizer system for stabilizing pvc CROMPTON VINYL ADDITIVES GMBH (DE) 2006-03-09 US disclosed
EP-1343838-B1 STABILIZER SYSTEM FOR STABILIZING POLYMERS THAT CONTAIN HALOGEN CROMPTON VINYL ADDITIVES GMBH (DE) 2005-04-06 EP disclosed
US-20040259988-A1 Prestabilization of halogen-containing polymers CHEMTURA VINYL ADDITIVES GMBH (DE) 2004-12-23 US disclosed
US-20040204522-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers AUSTEN STEVEN CHRISTOPHER (US) 2004-10-14 US disclosed
EP-1466941-A2 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM AND HAAS COMPANY (US) 2004-10-13 EP disclosed
EP-1461375-A1 PRESTABILIZATION OF HALOGEN-CONTAINING POLYMERS Crompton Vinyl Additives GmbH (DE) 2004-09-29 EP disclosed
US-20040054043-A1 Stabilizer system for stabilizing polymers that contain halogen WACHOVIA CAPITAL FINANCE CORPORATION (NEW ENGLAND) 2004-03-18 US disclosed
WO-2003048232-A1 PRESTABILIZATION OF HALOGEN-CONTAINING POLYMERS CROMPTON VINYL ADDITIVES GMBH (DE) 2003-06-12 WO disclosed
WO-2003048233-A1 STABILIZATION OF DISPERSIONS OF HALOGEN-CONTAINING POLYMERS CROMPTON VINYL ADDITIVES GMBH (DE) 2003-06-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10829718-B2 Detergent composition comprising a carbinol functional trisiloxane DEGS1, MSMO1, F12 USP2 643/4885ALDH1A1 4140/4885HTT 4106/4885
US-20190112549-A1 DETERGENT COMPOSITION COMPRISING A CARBINOL FUNCTIONAL TRISILOXANE DEGS1, MSMO1, F12 USP2 643/4885ALDH1A1 4140/4885HTT 4106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.