Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | KDM6B | O15054 | 1/20 | 0.51 |
| ▸ | KDM6A | O15550 | 1/20 | 0.51 |
| ▸ | UTRN | P46939 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2138741 | 0.87 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL28395976 | 0.84 | MAPT (0.55) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL7578683 | 0.84 | ESR1 (0.52) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL11696610 | 0.84 | HPGD (0.55) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL3257379 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL31048496 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL11697912 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL10829813 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL10829817 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL12263220 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773248-B1 | Polymers with heterocyclic side groups | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2002-10-02 | — | — | EP | disclosed |
| US-5668245-A | PHENYLENE POLYMERS WITH HETEROCYCLIC SIDE GROUPS | MAXDEM INCORPORATED (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0773248-A1 | Polymers with heterocyclic side groups | MAXDEM INCORPORATED (US) | 1997-05-14 | — | — | EP | disclosed |