Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5616687 | 0.90 | CYP3A4 (0.34) | CYP3A4CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL10359709 | 0.90 | ESR1 (0.40) | CYP3A4CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL10416758 | 0.89 | NPC1 (0.48) | CYP3A4CYP2C9CYP2C19ALOX5PTGS2 | |
| SCHEMBL5510301 | 0.89 | NPC1 (0.41) | CYP3A4CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL30393631 | 0.89 | NPC1 (0.45) | CYP3A4CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL6558920 | 0.89 | NPC1 (0.45) | CYP3A4CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL712969 | 0.89 | NPC1 (0.38) | CYP3A4CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL29706577 | 0.89 | NPC1 (0.38) | CYP3A4CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL769171 | 0.87 | NPC1 (0.36) | CYP3A4CYP1A2CYP2C9TSHRCYP2C19 | |
| SCHEMBL29358608 | 0.87 | NPC1 (0.36) | CYP3A4CYP1A2CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861813-A | 5-Aralkyl substituted 2h-benzotriazoles in stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1989-08-29 | — | — | US | claimed |
| US-4760148-A | 5-aralkyl substituted 2H-benzotriazoles and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | claimed |
| EP-0309401-B2 | Stabilization of coatings with N-hydroxy hindered amines | CIBA SC HOLDING AG (CH) | 2002-06-05 | — | — | EP | disclosed |
| EP-0309401-B1 | Stabilization of coatings with N-hydroxy hindered amines | CIBA GEIGY AG (CH) | 1994-10-26 | — | — | EP | disclosed |
| EP-0593936-A1 | N-[2-hydroxy-3-(2H-benzotriazol-2-yl)benzyl]oxamides as light stabilisers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-04-27 | — | — | EP | disclosed |
| US-5006577-A | Durable, weatherproof | CIBA-GEIGY CORPORATION (US) | 1991-04-09 | — | — | US | disclosed |
| US-4861813-A | 5-Aralkyl substituted 2h-benzotriazoles in stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |
| US-4861813-A | 5-Aralkyl substituted 2h-benzotriazoles in stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0309401-A1 | Stabilization of coatings with N-hydroxy hindered amines | CIBA-GEIGY AG (CH) | 1989-03-29 | — | — | EP | disclosed |
| US-4760148-A | 5-aralkyl substituted 2H-benzotriazoles and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |
| US-4760148-A | 5-aralkyl substituted 2H-benzotriazoles and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |