Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358608 | 1.00 | NPC1 (0.36) | NPC1RAB9AKDM4EPOLBCYP3A4 | |
| SCHEMBL5616687 | 0.96 | CYP3A4 (0.34) | NPC1RAB9AKDM4EPOLBCYP3A4 | |
| SCHEMBL29376453 | 0.94 | NPC1 (0.36) | NPC1RAB9AKDM4EPOLBCYP3A4 | |
| SCHEMBL769298 | 0.94 | NPC1 (0.36) | NPC1RAB9AKDM4EPOLBCYP3A4 | |
| SCHEMBL6860602 | 0.90 | DHODH (0.36) | NPC1RAB9AKDM4ECYP3A4PKM | |
| SCHEMBL29357978 | 0.89 | NPC1 (0.33) | NPC1RAB9AKDM4EPOLBCYP3A4 | |
| SCHEMBL225355 | 0.89 | NPC1 (0.33) | NPC1RAB9AKDM4EPOLBCYP3A4 | |
| SCHEMBL768944 | 0.88 | KDM4E (0.38) | NPC1RAB9AKDM4EPOLBCYP3A4 | |
| SCHEMBL29358804 | 0.88 | KDM4E (0.38) | NPC1RAB9AKDM4EPOLBCYP3A4 | |
| SCHEMBL1499910 | 0.88 | NPC1 (0.45) | NPC1RAB9AKDM4EPOLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 661 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391949-B1 | — | — | None | — | — | US | claimed |
| JP-4705249-B2 | — | — | 2011-06-22 | — | — | JP | claimed |
| US-7288583-B2 | Method of content protection with durable UV absorbers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-10-30 | — | — | US | claimed |
| EP-1175467-B1 | STABILIZED ADHESIVE COMPOSITIONS CONTAINING HIGHLY SOLUBLE, RED-SHIFTED, PHOTOSTABLE BENZOTRIAZOLE UV ABSORBERS AND LAMINATED ARTICLES DERIVED THEREFROM | CIBA SC HOLDING AG (CH) | 2006-06-14 | — | — | EP | claimed |
| US-20050123691-A1 | Photo-cured and stabilized coatings | SUHADOLNIK JOSEPH (US) | 2005-06-09 | — | — | US | claimed |
| CN-1186417-C | Stabilized adhesive compositions containing highly soluble, red-shifted, photostable benzotriazole UV absorbers and laminates made therefrom | CIBA SC HOLDING AG (CH) | 2005-01-26 | — | — | CN | claimed |
| US-6800676-B2 | ULTRAVIOLET RADIATION ABSORBERS; HEAT AND OXIDATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-10-05 | — | — | US | claimed |
| US-20040191447-A1 | storage of food, beverages, drugs or cosmetics in radiation transparent plastic containers having coatings comprising stabilizer agents selected from hydroxyphenyl benzotriazole ultraviolet radiation absorber materials | ANDREWS STEPHEN M (US) | 2004-09-30 | — | — | US | claimed |
| US-6797751-B2 | A CLEAR OR LIGHTLY COLORED PLASTIC CONTAINERS OR FILMS COMPRISING A BENZOTRIAZOLES OR TRIS-ARYL-S-TRIAZINES STABILIZER; PROTECTIVE DEVICES FOR FOODS, BEVERAGES, DRUGS, COSMETICS, SHAMPOO | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-09-28 | — | — | US | claimed |
| EP-1448613-A1 | CURABLE MIXTURES COMPRISING UV-ABSORBER, ACYLPHOSPHINOXIDE AND HYDROXY KETONE PHOTOINITIATOR | Ciba SC Holding AG (CH) | 2004-08-25 | — | — | EP | claimed |
| EP-1175467-A1 | STABILIZED ADHESIVE COMPOSITIONS CONTAINING HIGHLY SOLUBLE, RED-SHIFTED, PHOTOSTABLE BENZOTRIAZOLE UV ABSORBERS AND LAMINATED ARTICLES DERIVED THEREFROM | Ciba SC Holding AG (CH) | 2002-01-30 | — | — | EP | claimed |
| US-20010034449-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-10-25 | — | — | US | claimed |
| US-20010031872-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-10-18 | — | — | US | claimed |
| US-6296674-B1 | Candle wax stabilized with red-shift benzotriazoles | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-10-02 | — | — | US | claimed |
| US-20010018520-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-08-30 | — | — | US | claimed |
| WO-2001057125-A1 | CANDLE WAX STABILIZED WITH RED-SHIFTED BENZOTRIAZOLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-08-09 | — | — | WO | claimed |
| US-6268415-B1 | POLYMERS AND STABILIZERS FOR ENHANCED STABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-31 | — | — | US | claimed |
| US-6262151-B1 | FOR AUTOMOTIVE COATINGS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-17 | — | — | US | claimed |
| US-6187845-B1 | LAMINATION OR MULTILAYER STRUCTURE | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-02-13 | — | — | US | claimed |
| WO-2000066676-A1 | STABILIZED ADHESIVE COMPOSITIONS CONTAINING HIGHLY SOLUBLE, RED-SHIFTED, PHOTOSTABLE BENZOTRIAZOLE UV ABSORBERS AND LAMINATED ARTICLES DERIVED THEREFROM | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-11-09 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034449-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | NPC1 1790/4885RAB9A 2188/4885KDM4E 1548/4885 |
| US-20010018520-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | NPC1 1790/4885RAB9A 2188/4885KDM4E 1548/4885 |
| US-20010031872-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | NPC1 1790/4885RAB9A 2188/4885KDM4E 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.