Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16259120 | 0.70 | HSP90AA1 (0.33) | HSP90AA1 | |
| SCHEMBL29168794 | 0.70 | KDM4E (0.30) | — | |
| SCHEMBL174733 | 0.70 | CYP11B1 (0.33) | — | |
| SCHEMBL444756 | 0.62 | CYP3A4 (0.55) | — | |
| SCHEMBL4722334 | 0.62 | — | — | |
| SCHEMBL2805287 | 0.60 | HSP90AA1 (0.33) | HSP90AA1 | |
| SCHEMBL2605832 | 0.60 | — | — | |
| SCHEMBL2747913 | 0.59 | HSP90AA1 (0.32) | HSP90AA1 | |
| SCHEMBL6428658 | 0.59 | CYP1A2 (0.43) | — | |
| SCHEMBL7085644 | 0.58 | PTPRA (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002096361-A2 | 5-ARALKYLSULFONYL-3- (PYRROL-2-YLMETHYLIDENE)-2-INDOLINONE DERIVATIVES AS KINASE INHIBITORS | SUGEN, INC. (US) | 2002-12-05 | — | — | WO | disclosed |