Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962293 | 0.78 | HTT (0.47) | TSHRCA2P2RX7HTT | |
| SCHEMBL28182827 | 0.78 | ALDH1A1 (0.34) | ALDH1A1CYP3A4KDM4EMAPTP2RX7 | |
| SCHEMBL874090 | 0.77 | CYP1A2 (0.50) | CYP1A2GABRA5GABRB2GABRA1GABRA4 | |
| SCHEMBL17866361 | 0.76 | KEAP1 (0.41) | ALDH1A1HSD17B10P4HTM | |
| Hydrochloric Acid SCHEMBL6645397 | 0.75 | KDM4E (0.48) | CYP1A2GABRA5GABRB2GABRA1GABRA4 | |
| SCHEMBL24786402 | 0.73 | CA2 (0.43) | CYP1A2GABRA5GABRB2GABRA1GABRA4 | |
| SCHEMBL7499590 | 0.73 | GABRA1 (0.53) | CYP1A2GABRA5GABRB2GABRA1GABRA4 | |
| SCHEMBL28048188 | 0.72 | EGLN1 (0.43) | CYP1A2GABRA5GABRB2GABRA1GABRA4 | |
| SCHEMBL17973028 | 0.71 | AGBL2 (0.43) | CYP1A2GABRA5GABRB2GABRA1GABRA4 | |
| SCHEMBL18860995 | 0.71 | ALDH1A1 (0.42) | CYP1A2GABRA5GABRB2GABRA1GABRA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422751-B1 | Substituted 2-pyrimidinyl and 2-triazinylacetic acid derivatives, process for their preparation and their use as agent with herbicidal, fungicidal and plant growth regulating activity | HOECHST SCHERING AGREVO GMBH (DE) | 1996-08-14 | — | — | EP | claimed |
| US-5098465-A | Triazine or pyrimidine acetic acids or amides | SHERING AKTIENGESELLSCHAFT (DE) | 1992-03-24 | — | — | US | claimed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| WO-2005024755-A2 | MEDICAMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS OR DIABETES | DECIPHERA PHARMACEUTICALS, LLC. (US) | 2005-03-17 | — | — | WO | disclosed |
| US-5604181-A | Pyrimidine derivatives herbicides | AGREVO UK LIMITED (GB) | 1997-02-18 | — | — | US | disclosed |
| EP-0422751-B1 | Substituted 2-pyrimidinyl and 2-triazinylacetic acid derivatives, process for their preparation and their use as agent with herbicidal, fungicidal and plant growth regulating activity | HOECHST SCHERING AGREVO GMBH (DE) | 1996-08-14 | — | — | EP | disclosed |
| US-5502028-A | Herbicidal pyrimidinyl or triazinyl haloacetic acid derivatives | SCHERING AGROCHEMICALS LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |
| EP-0660829-A1 | PYRIMIDINE DERIVATIVE HERBICIDES | AgrEvo UK Limited (GB) | 1995-07-05 | — | — | EP | disclosed |
| US-5317005-A | Pyrimidinyl and triazinyl herbicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1994-05-31 | — | — | US | disclosed |
| WO-1994005644-A1 | PYRIMIDINE DERIVATIVE HERBICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1994-03-17 | — | — | WO | disclosed |
| EP-0575404-A1 | HERBICIDES | AgrEvo UK Limited (GB) | 1993-12-29 | — | — | EP | disclosed |
| US-5238907-A | Substituted 2-pyrimidinyl-acetic acid derivatives, and their use as herbicides, fungicides and plant growth regulators | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-08-24 | — | — | US | disclosed |
| US-5238907-A | Substituted 2-pyrimidinyl-acetic acid derivatives, and their use as herbicides, fungicides and plant growth regulators | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-08-24 | — | — | US | disclosed |
| EP-0539427-A1 | PYRIMIDINYL AND TRIAZINYL HERBICIDES | AgrEvo UK Limited (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1992016511-A1 | HERBICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-10-01 | — | — | WO | disclosed |
| US-5098465-A | Triazine or pyrimidine acetic acids or amides | SHERING AKTIENGESELLSCHAFT (DE) | 1992-03-24 | — | — | US | disclosed |
| US-5098465-A | Triazine or pyrimidine acetic acids or amides | SHERING AKTIENGESELLSCHAFT (DE) | 1992-03-24 | — | — | US | disclosed |
| WO-1992001677-A1 | PYRIMIDINYL AND TRIAZINYL HERBICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-02-06 | — | — | WO | disclosed |
| EP-0422751-A2 | Substituted 2-pyrimidinyl and 2-triazinylacetic acid derivatives, process for their preparation and their use as agent with herbicidal, fungicidal and plant growth regulating activity | Hoechst Schering AgrEvo GmbH (DE) | 1991-04-17 | — | — | EP | disclosed |