Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 14/20 | 0.65 |
| ▸ | ACE | P12821 | 12/20 | 0.65 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.47 |
| ▸ | CPA1 | P15085 | 4/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570111 | 0.94 | MME (0.62) | MMEACEACE2CPA1PSEN1 | |
| SCHEMBL7568216 | 0.94 | MME (0.62) | MMEACEACE2CPA1PSEN1 | |
| SCHEMBL7566971 | 0.93 | MME (0.66) | MMEACEACE2CPA1PSEN1 | |
| SCHEMBL7572812 | 0.93 | MME (0.61) | MMEACEACE2CPA1PSEN1 | |
| SCHEMBL8452236 | 0.91 | MME (0.53) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL8450793 | 0.90 | MME (0.54) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL8017187 | 0.89 | MME (0.78) | MMEACEACE2CPA1PSEN1 | |
| SCHEMBL7569066 | 0.88 | MME (0.67) | MMEACEACE2CPA1 | |
| SCHEMBL7569072 | 0.88 | MME (0.67) | MMEACEACE2CPA1 | |
| SCHEMBL8449852 | 0.88 | MME (0.54) | MMEACEPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |