Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.62 |
| ▸ | ACE | P12821 | 12/20 | 0.62 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.45 |
| ▸ | CPA1 | P15085 | 3/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572812 | 0.97 | MME (0.61) | MMEACEMMP1MMP3MMP9 | |
| SCHEMBL7570111 | 0.96 | MME (0.62) | MMEACEMMP1MMP3MMP9 | |
| SCHEMBL7574113 | 0.94 | MME (0.65) | MMEACEACE2CPA1PSEN1 | |
| SCHEMBL7566971 | 0.93 | MME (0.66) | MMEACEACE2CPA1PSEN1 | |
| SCHEMBL8449459 | 0.92 | MME (0.52) | MMEACEMMP1MMP3MMP9 | |
| SCHEMBL8446468 | 0.90 | MME (0.51) | MMEACEMMP1MMP3MMP9 | |
| SCHEMBL7565980 | 0.90 | MME (0.70) | MMEACEMMP1MMP3ACE2 | |
| SCHEMBL7565973 | 0.90 | MME (0.70) | MMEACEMMP1MMP3ACE2 | |
| SCHEMBL8451289 | 0.89 | MME (0.52) | MMEACEMMP1MMP3MMP9 | |
| SCHEMBL7567643 | 0.89 | MME (0.52) | MMEACEMMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |