Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.49 |
| ▸ | LTA4H | P09960 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574268 | 0.91 | LTA4H (0.47) | ESR1ESR2LTA4HHTTKDM4E | |
| SCHEMBL7580976 | 0.90 | ESR1 (0.52) | ESR1ESR2LTA4HHTT | |
| SCHEMBL7580211 | 0.87 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL7575042 | 0.83 | LTA4H (0.51) | ESR1ESR2LTA4HHTT | |
| SCHEMBL7573215 | 0.81 | ESR1 (0.53) | ESR1ESR2 | |
| SCHEMBL7582587 | 0.81 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL7582528 | 0.80 | LTA4H (0.49) | ESR1ESR2LTA4H | |
| SCHEMBL7582157 | 0.79 | ESR1 (0.49) | ESR1ESR2LTA4H | |
| SCHEMBL6142894 | 0.77 | ESR1 (0.52) | ESR1ESR2LTA4HHTTKDM4E | |
| SCHEMBL6142890 | 0.77 | ESR1 (0.52) | ESR1ESR2LTA4HHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994370-A | ESTROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 1999-11-30 | — | — | US | claimed |
| EP-0873992-B1 | Indene compounds having activity as SERMs | LILLY CO ELI (US) | 2002-09-25 | — | — | EP | disclosed |
| US-5994370-A | ESTROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 1999-11-30 | — | — | US | disclosed |
| EP-0873992-A1 | Indene compounds having activity as SERMs | ELI LILLY AND COMPANY (US) | 1998-10-28 | — | — | EP | disclosed |