⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2182873 | 0.78 | — | — | |
| SCHEMBL5960912 | 0.75 | — | — | |
| SCHEMBL2216493 | 0.72 | — | — | |
| SCHEMBL2180988 | 0.72 | — | — | |
| SCHEMBL1776917 | 0.71 | — | — | |
| SCHEMBL29601 | 0.71 | — | — | |
| SCHEMBL3062549 | 0.69 | — | — | |
| Methane SCHEMBL16463501 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL11428331 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL11037230 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751948-B1 | NOVEL PHOSPHORAMIDATE AND PHOPHOROTHIOAMIDATE OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 2002-09-25 | — | — | EP | disclosed |
| US-5717083-A | COMPLEXING WITH PROTEINS, NUCLEIC ACIDS, LIPIDS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-10 | — | — | US | disclosed |
| US-5637684-A | BINDING PROTEINS, NUCLEIC ACIDS, LIPIDS; PHOSPHOLIPASE INHIBITOR | ISIS PHARMACEUTICALS, INC. (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0751948-A4 | NOVEL PHOSPHORAMIDATE AND PHOPHOROTHIOAMIDATE OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0751948-A1 | NOVEL PHOSPHORAMIDATE AND PHOPHOROTHIOAMIDATE OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995023160-A1 | NOVEL PHOSPHORAMIDATE AND PHOPHOROTHIOAMIDATE OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1995-08-31 | — | — | WO | disclosed |