Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HBB | P68871 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.37 |
| ▸ | KDM4A | O75164 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 3/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725597 | 0.91 | LMNA (0.48) | BLMMEN1LMNAHBBKMT2A | |
| SCHEMBL23429896 | 0.83 | LMNA (0.41) | BLMMEN1LMNAHBBKMT2A | |
| SCHEMBL7694858 | 0.82 | HDAC1 (0.41) | BLMMEN1LMNAHBBKMT2A | |
| SCHEMBL23429927 | 0.82 | LMNA (0.44) | BLMMEN1LMNAHBBKMT2A | |
| SCHEMBL23429936 | 0.80 | LMNA (0.46) | LMNAENPEPALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL23429951 | 0.80 | LMNA (0.46) | LMNAENPEPALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL23429918 | 0.80 | LMNA (0.46) | LMNAENPEPALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL23429924 | 0.80 | LMNA (0.46) | LMNAENPEPALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL23429903 | 0.80 | LMNA (0.46) | LMNAENPEPALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL23429922 | 0.80 | LMNA (0.46) | LMNAENPEPALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6461856-B2 | NUCLEOTIDE SQUENCES CODING DEHYDROGENASE; FOR USE IN POLLUTION CONTROL | E. I. DU PONT DE NEMOURS & COMPANY | 2002-10-08 | — | — | US | disclosed |
| US-20020042117-A1 | Genes encoding picric acid degradation | ROUVIERE PIERRE E (US) | 2002-04-11 | — | — | US | disclosed |
| US-6355470-B1 | Genes encoding picric acid degradation | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-03-12 | — | — | US | disclosed |