Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8261303 | 0.79 | TDP1 (0.43) | MEN1KMT2ATDP1SLC9A3TP53 | |
| SCHEMBL7581821 | 0.78 | ALDH1A1 (0.42) | MEN1KMT2ATDP1TP53MAPT | |
| SCHEMBL7579202 | 0.73 | GRIN2D (0.41) | TDP1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL9550627 | 0.72 | TDP1 (0.44) | MEN1KMT2ATDP1SLC9A3TP53 | |
| SCHEMBL7572617 | 0.71 | TP53 (0.46) | MEN1KMT2ATDP1SLC9A3TP53 | |
| SCHEMBL1927493 | 0.70 | KMT2A (0.58) | MEN1KMT2ATDP1TP53GABRA1 | |
| SCHEMBL24496899 | 0.69 | TDP1 (0.41) | MEN1KMT2ATDP1SLC9A3TP53 | |
| SCHEMBL14402929 | 0.69 | TDP1 (0.41) | MEN1KMT2ATDP1SLC9A3TP53 | |
| SCHEMBL17225192 | 0.69 | TDP1 (0.41) | MEN1KMT2ATDP1SLC9A3TP53 | |
| SCHEMBL6392202 | 0.69 | SLC9A3 (0.44) | MEN1KMT2ATDP1SLC9A3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |