Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473682 | 0.85 | EGFR (0.49) | EGFRALDH1A1TP53SMN1; SMN2TDP1 | |
| SCHEMBL2475921 | 0.85 | EGFR (0.49) | EGFRALDH1A1TP53SMN1; SMN2TDP1 | |
| SCHEMBL12473677 | 0.85 | EGFR (0.49) | EGFRALDH1A1TP53SMN1; SMN2TDP1 | |
| SCHEMBL30480358 | 0.85 | EGFR (0.49) | EGFRALDH1A1TP53SMN1; SMN2TDP1 | |
| SCHEMBL2488995 | 0.82 | EGFR (0.58) | EGFRHDAC1HDAC6HDAC5 | |
| SCHEMBL31537010 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL1715242 | 0.79 | ALDH1A1 (0.71) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL7966245 | 0.78 | ALDH1A1 (0.57) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL7966243 | 0.78 | ALDH1A1 (0.57) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL7966244 | 0.78 | ALDH1A1 (0.57) | ALDH1A1TP53TSHRHIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002092577-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2002-11-21 | — | — | WO | disclosed |