Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL30698150 | 0.91 | SLC22A1 (0.50) | SLC22A1DNM1SLC22A2CA1CES2 | |
| Tetrabuthylammonium SCHEMBL109269 | 0.90 | SLC22A1 (0.63) | SLC22A1DNM1SLC22A2CES2CES1 | |
| Tetrabuthylammonium SCHEMBL9315609 | 0.90 | SLC22A1 (0.63) | SLC22A1DNM1SLC22A2CES2CES1 | |
| Bicarbonate SCHEMBL2275966 | 0.88 | DNM1 (0.56) | SLC22A1DNM1SLC22A2CA1CES2 | |
| Tetrabuthylammonium SCHEMBL9315602 | 0.88 | SLC22A1 (0.60) | SLC22A1DNM1SLC22A2CES2CES1 | |
| Bicarbonate SCHEMBL29201411 | 0.86 | SLC22A1 (0.62) | SLC22A1DNM1SLC22A2CES2CES1 | |
| Tetrabuthylammonium SCHEMBL16093912 | 0.86 | SLC22A1 (0.57) | SLC22A1DNM1SLC22A2CES2CES1 | |
| Acetic Acid SCHEMBL30698142 | 0.86 | SLC22A1 (0.50) | SLC22A1DNM1SLC22A2CA1CES2 | |
| Acetic Acid SCHEMBL21384662 | 0.86 | DNM1 (0.54) | SLC22A1DNM1SLC22A2CA1CES2 | |
| Tetrabuthylammonium SCHEMBL5786104 | 0.86 | SLC22A1 (0.57) | SLC22A1DNM1SLC22A2CA1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4717720-A1 | CATALYST COMPOSITION, BLOCKED POLYISOCYANATE COMPOSITION, COATING MATERIAL COMPOSITION, COATING FILM, AND METHOD FOR FORMING COATING FILM | Tosoh Corporation (JP) | 2026-04-01 | — | — | EP | disclosed |
| EP-4692150-A1 | CURABLE COMPOSITION AND CURED PRODUCT OF SAME | DIC Corporation (JP) | 2026-02-11 | — | — | EP | disclosed |
| EP-4678676-A1 | BLOCKED POLYISOCYANATE COMPOSITION, CURING AGENT FOR AQUEOUS COATING, AQUEOUS COATING COMPOSITION, AND COATING FILM | Tosoh Corporation (JP) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024262553-A1 | CATALYST COMPOSITION, BLOCKED POLYISOCYANATE COMPOSITION, COATING MATERIAL COMPOSITION, COATING FILM, AND METHOD FOR FORMING COATING FILM | 東ソー株式会社 | 2024-12-26 | — | — | WO | disclosed |
| WO-2024209935-A1 | CURABLE COMPOSITION AND CURED PRODUCT OF SAME | DIC株式会社 | 2024-10-10 | — | — | WO | disclosed |
| WO-2024202500-A1 | BLOCKED POLYISOCYANATE COMPOSITION, CURING AGENT FOR AQUEOUS COATING, AQUEOUS COATING COMPOSITION, AND COATING FILM | 東ソー株式会社 | 2024-10-03 | — | — | WO | disclosed |
| EP-0999206-B1 | Process for producing alpha cyano acetic acid esters | BASF AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| EP-0999206-A1 | Process for producing alpha cyano acetic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-10 | — | — | EP | disclosed |