Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 15/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 15/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 13/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223913 | 1.00 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL7124547 | 0.92 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL7127767 | 0.86 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL7223878 | 0.83 | CHRNA7 (0.42) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL7120484 | 0.82 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL7121506 | 0.82 | ACKR3 (0.39) | — | |
| SCHEMBL7131778 | 0.82 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL7597719 | 0.82 | ACKR3 (0.39) | — | |
| SCHEMBL7125448 | 0.80 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL7121119 | 0.80 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002015662-A2 | QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |