Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21143038 | 0.86 | HPGD (0.40) | ELANEKMT2ALMNATSHRMEN1 | |
| SCHEMBL7524562 | 0.83 | CYP2C19 (0.45) | KMT2ARAB9AMAPTLMNATSHR | |
| SCHEMBL2392777 | 0.83 | ELANE (0.41) | ELANEATMMAPTLMNAALDH1A1 | |
| SCHEMBL3257932 | 0.82 | AR (0.33) | MAPTLMNATSHRTDP1ALDH1A1 | |
| SCHEMBL1232007 | 0.79 | ELANE (0.57) | ELANEKMT2AATMRAB9AMAPT | |
| SCHEMBL19540354 | 0.79 | ELANE (0.57) | ELANEKMT2AATMRAB9AMAPT | |
| SCHEMBL14173266 | 0.79 | ELANE (0.57) | ELANEKMT2AATMRAB9AMAPT | |
| SCHEMBL56436 | 0.78 | ELANE (0.69) | ELANEKMT2AATMRAB9AMAPT | |
| SCHEMBL3135520 | 0.77 | ELANE (0.56) | ELANEKMT2AATMRAB9AMAPT | |
| SCHEMBL10870371 | 0.76 | ELANE (0.51) | ELANEKMT2AATMRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795765-B1 | Photopolymerizable composition and transparent cured product thereof | TOKUYAMA CORP (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5880170-A | TRANSPARENT LENSES FORMED BY CURING | TOKUYAMA CORPORATION (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0795765-A2 | Photopolymerizable composition and transparent cured product thereof | TOKUYAMA CORPORATION (JP) | 1997-09-17 | — | — | EP | disclosed |