Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 10/20 | 0.62 |
| ▸ | ACE | P12821 | 9/20 | 0.62 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 3/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | FCER2 | P06734 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573208 | 0.94 | MME (0.64) | MMEACECTSBCPA1ACE2 | |
| SCHEMBL7567474 | 0.93 | MME (0.72) | MMEACECPA1ACE2 | |
| SCHEMBL8447317 | 0.87 | MME (0.56) | MMEACECTSB | |
| SCHEMBL7570511 | 0.87 | MME (0.55) | MMEACECTSBHPGDSFCER2 | |
| SCHEMBL8029449 | 0.86 | MME (0.76) | MMEACECPA1ACE2HPGDS | |
| SCHEMBL8029444 | 0.86 | MME (0.76) | MMEACECPA1ACE2HPGDS | |
| SCHEMBL8447819 | 0.85 | MME (0.85) | MMEACECPA1ACE2 | |
| SCHEMBL8017720 | 0.85 | MME (0.85) | MMEACECPA1ACE2 | |
| SCHEMBL8017716 | 0.85 | MME (0.85) | MMEACECPA1ACE2 | |
| SCHEMBL7567925 | 0.85 | MME (0.77) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |