Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29850702 | 0.81 | DAO (0.46) | MEN1KMT2ATSHRALOX15ALDH1A1 | |
| SCHEMBL2995033 | 0.81 | DAO (0.46) | MEN1KMT2ATSHRALOX15ALDH1A1 | |
| SCHEMBL29519621 | 0.80 | NPC1 (0.57) | NPC1RAB9AALOX15EGFRPIK3CA | |
| SCHEMBL14311952 | 0.78 | BACE1 (0.39) | MAP2K1TSHREGFR | |
| SCHEMBL29519596 | 0.78 | BACE1 (0.39) | MAP2K1TSHREGFR | |
| Hydrochloric Acid SCHEMBL30991388 | 0.76 | BACE1 (0.39) | MAP2K1TSHREGFR | |
| SCHEMBL28021323 | 0.74 | NUDT1 (0.46) | ALOX15EGFR | |
| SCHEMBL18969568 | 0.74 | ABL1 (0.47) | CYP1A2ABL1 | |
| SCHEMBL28519107 | 0.73 | BACE1 (0.35) | EGFRABL1 | |
| SCHEMBL29617789 | 0.73 | FGFR1 (0.43) | CYP1A2CYP3A4ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020061896-A1 | Imidazopyrimidine nucleoside analogues with anti-HIV activity | BIOCHEM PHARMA, INC. (CA) | 2002-05-23 | — | — | US | disclosed |
| WO-2001049700-A1 | IMIDAZOPYRIMIDINE NUCLEOSIDE ANALOGUES WITH ANTI-HIV ACTIVITY | BIOCHEM PHARMA INC. (CA) | 2001-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061896-A1 | Imidazopyrimidine nucleoside analogues with anti-HIV activity | TYMP, PNP, SLC29A1 | MAP2K1 3452/4885MEN1 3208/4885KMT2A 2945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.