Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 7/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.33 |
| ▸ | DHODH | Q02127 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115295 | 0.90 | PDE4D (0.35) | PDE4DNR1H4DHODHPDE4B | |
| SCHEMBL9116511 | 0.88 | DHODH (0.34) | NR1H4DHODHALDH1A1HPGDPDE2A | |
| SCHEMBL7575625 | 0.87 | DHODH (0.33) | DHODHPDE2A | |
| SCHEMBL7577256 | 0.85 | DHODH (0.32) | DHODHPDE2A | |
| SCHEMBL7575595 | 0.85 | DHODH (0.33) | DHODHPDE2A | |
| SCHEMBL7572977 | 0.85 | PDE4D (0.35) | PDE4DNR1H4DHODHPDE4B | |
| SCHEMBL8729861 | 0.84 | PDE4B (0.34) | PDE4DNR1H4DHODHPDE4BALDH1A1 | |
| SCHEMBL7576281 | 0.84 | PDE4D (0.33) | PDE4DNR1H4DHODHPDE4BPDE2A | |
| SCHEMBL9116932 | 0.84 | DHODH (0.35) | PDE4DDHODHPDE4BALDH1A1HPGD | |
| SCHEMBL7583005 | 0.83 | DHODH (0.32) | DHODHPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | claimed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | claimed |
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| US-5374606-A | Pre- and postemergence | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |