Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575354 | 0.88 | DHODH (0.35) | NR1H4DHODH | |
| SCHEMBL9115295 | 0.87 | PDE4D (0.35) | PDE4DNR1H4DHODHPDE4B | |
| SCHEMBL7575598 | 0.85 | DHODH (0.33) | NR1H4DHODH | |
| SCHEMBL7575367 | 0.85 | PDE4D (0.34) | PDE4DNR1H4DHODHPDE4B | |
| SCHEMBL8729870 | 0.85 | DHODH (0.33) | PDE4DNR1H4DHODHPDE4B | |
| SCHEMBL7573255 | 0.84 | DHODH (0.32) | NR1H4DHODH | |
| SCHEMBL7577830 | 0.84 | DHODH (0.32) | NR1H4DHODH | |
| SCHEMBL7576281 | 0.83 | PDE4D (0.33) | PDE4DNR1H4DHODHPDE4B | |
| SCHEMBL9116932 | 0.83 | DHODH (0.35) | PDE4DDHODHMAPTPDE4B | |
| SCHEMBL8491946 | 0.82 | DHODH (0.33) | PDE4DNR1H4DHODHPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | claimed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | claimed |
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| US-5374606-A | Pre- and postemergence | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |