Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.59 |
| ▸ | ACE | P12821 | 6/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 4/20 | 0.48 |
| ▸ | MMP8 | P22894 | 4/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.48 |
| ▸ | MMP12 | P39900 | 2/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | FCER2 | P06734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567465 | 0.95 | MME (0.66) | MMEACEMMP9MMP2MMP12 | |
| SCHEMBL7575021 | 0.95 | MME (0.60) | MMEACEHDAC3HDAC4HDAC1 | |
| SCHEMBL7567456 | 0.95 | MME (0.66) | MMEACEMMP9MMP2MMP12 | |
| SCHEMBL8447140 | 0.89 | MMP3 (0.52) | MMEACEMMP9MMP12CPA1 | |
| SCHEMBL7567643 | 0.89 | MME (0.52) | MMEACEHDAC3HDAC4HDAC1 | |
| SCHEMBL7570067 | 0.88 | MME (0.70) | MMEACEMMP9MMP2MMP12 | |
| SCHEMBL7570068 | 0.88 | MME (0.70) | MMEACEMMP9MMP2MMP12 | |
| SCHEMBL7566363 | 0.87 | MME (0.71) | MMEACEMMP9MMP2MMP12 | |
| SCHEMBL7566359 | 0.87 | MME (0.71) | MMEACEMMP9MMP2MMP12 | |
| SCHEMBL7572401 | 0.87 | MME (0.71) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |