Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3432262 | 0.89 | KCNN4 (0.46) | KCNN4PGRARGAAPOLB | |
| SCHEMBL1133173 | 0.85 | KCNN4 (0.54) | KCNN4PGRARGAAPOLB | |
| SCHEMBL8718691 | 0.83 | MAOA (0.53) | ARGAAPOLBKDM4EALDH1A1 | |
| SCHEMBL11132592 | 0.81 | ESR2 (0.43) | GAAKDM4EALDH1A1MAOAMAOB | |
| SCHEMBL28408790 | 0.79 | POLB (0.51) | ARGAAPOLBKDM4EALDH1A1 | |
| SCHEMBL11876478 | 0.79 | ESR2 (0.48) | GAAKDM4EALDH1A1TSHRMEN1 | |
| SCHEMBL8802694 | 0.77 | KDM4E (0.48) | KCNN4PGRARGAAKDM4E | |
| SCHEMBL104280 | 0.77 | POLB (0.66) | PGRARGAAPOLBKDM4E | |
| SCHEMBL29518610 | 0.77 | POLB (0.66) | PGRARGAAPOLBKDM4E | |
| SCHEMBL18406710 | 0.77 | TSHR (0.57) | ARGAATSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002096913-A1 | SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES | GENTIAN AS (NO) | 2002-12-05 | — | — | WO | disclosed |