Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573986 | 0.91 | PDE2A (0.33) | NAMPTPDE2ADHODH | |
| SCHEMBL27297938 | 0.87 | NAMPT (0.31) | NAMPTPDE2ADHODH | |
| SCHEMBL7575155 | 0.83 | PDE2A (0.33) | NAMPTPDE2ADHODH | |
| SCHEMBL7573423 | 0.81 | DHODH (0.32) | PDE2ADHODH | |
| SCHEMBL7573706 | 0.81 | DHODH (0.32) | PDE2ADHODH | |
| SCHEMBL7575595 | 0.81 | DHODH (0.33) | NAMPTPDE2ADHODH | |
| SCHEMBL7577500 | 0.80 | PDE2A (0.32) | NAMPTPDE2ADHODH | |
| SCHEMBL7573455 | 0.80 | DHODH (0.34) | NAMPTPDE2ADHODH | |
| SCHEMBL27294090 | 0.80 | PDE2A (0.34) | NAMPTPDE2ADHODH | |
| SCHEMBL27286392 | 0.80 | PDE2A (0.32) | NAMPTPDE2ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | claimed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | claimed |
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| US-5374606-A | Pre- and postemergence | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |