SCHEMBL7576639

SCHEMBL7576639

CCCCCCCCCCCCCCCCCCCC(=O)OCC(O)COC(=O)CCCCCCCCCCCCCCCCCCC

nearest known ligand 0.83

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.83
KDM4E B2RXH2 1/20 0.83
DUSP3 P51452 1/20 0.83
MEN1 O00255 1/20 0.83
KMT2A Q03164 1/20 0.83
MAPT P10636 1/20 0.76
ENPP2 Q13822 6/20 0.76
LPAR1 Q92633 6/20 0.76
LPAR4 Q99677 3/20 0.76
LPAR5 Q9H1C0 3/20 0.76
LPAR2 Q9HBW0 3/20 0.76
LPAR3 Q9UBY5 3/20 0.76
LPAR6 P43657 2/20 0.76
DGKA P23743 2/20 0.69
ALDH1A1 P00352 1/20 0.68
TRPV1 Q8NER1 2/20 0.65
CES2 O00748 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11787098 1.00 LMNA (0.83) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL896977 1.00 LMNA (0.83) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL9463709 1.00 LMNA (0.83) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL3109961 1.00 LMNA (0.83) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL21660226 1.00 LMNA (0.83) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL3941258 1.00 LMNA (0.83) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL2734722 1.00 LMNA (0.83) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL17129723 1.00 LMNA (0.83) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL2183839 1.00 LMNA (0.83) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL19944297 1.00 LMNA (0.83) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002049457-A1 THE USE OF A NON-ABSORBABLE, NON-DIGESTIBLE LIPID FOR THE TREATMENT OF HYPERBILIRUBINEMIA THE PROCTER & GAMBLE COMPANY (US) 2002-06-27 WO claimed
EP-1216625-A1 The use of a non-absorbable, non-digestible lipid for the treatment of hyperbilirubinemia THE PROCTER & GAMBLE COMPANY (US) 2002-06-26 EP claimed
US-RE34617-E An edible, nonabsorbable, indigestible liquid sugar esterified by a fatty acid, a diarrhea prevention agent and fat-soluble vitamins; anticholesterol and lipemic agents; cooking shortenings THE PROCTER & GAMBLE COMPANY (US) 1994-05-24 US claimed
US-RE33996-E A nonabsorbable, nondigestable liquid polyester and an antianal leakage agent of fatty acids THE PROCTER & GAMBLE COMPANY (US) 1992-07-14 US claimed
US-4241054-A Detoxifying lipophilic toxins THE PROCTER & GAMBLE COMPANY (US) 1980-12-23 US claimed
US-4005196-A FATTY ACID ESTERS OF POLYOLS THE PROCTER & GAMBLE COMPANY (US) 1977-01-25 US claimed
US-4005195-A FATTY ACID ESTERS OF POLYOLS THE PROCTER & GAMBLE COMPANY (US) 1977-01-25 US claimed
WO-2002049457-A1 THE USE OF A NON-ABSORBABLE, NON-DIGESTIBLE LIPID FOR THE TREATMENT OF HYPERBILIRUBINEMIA THE PROCTER & GAMBLE COMPANY (US) 2002-06-27 WO disclosed
EP-1216625-A1 The use of a non-absorbable, non-digestible lipid for the treatment of hyperbilirubinemia THE PROCTER & GAMBLE COMPANY (US) 2002-06-26 EP disclosed
WO-1996006823-A1 DICARBOXYLIC ACID ESTER DERIVATIVES WITH A DIACYLOXYPROPYL RESIDUE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-03-07 WO disclosed
US-5225590-A Alkoxy methyl ether and alkoxy methyl ester derivatives SYNTEX (U.S.A.) INC. (US) 1993-07-06 US disclosed
EP-0295092-B1 SKIN TREATMENT COMPOSITION UNILEVER PLC (GB) 1992-09-23 EP disclosed
EP-0187297-B1 ALKOXY METHYL ETHER AND ALKOXY METHYL ESTER DERIVATIVES SYNTEX (U.S.A.) INC. (US) 1991-08-21 EP disclosed
WO-1991007168-A1 RIBOFLAVIN AS A TANNING ENHANCER SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) 1991-05-30 WO disclosed
WO-1991007167-A1 PROTEIN KINASE ACTIVATORS AS ENHANCERS OF MELANIN PRODUCTION SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) 1991-05-30 WO disclosed
EP-0295092-A2 Skin treatment composition UNILEVER PLC (GB) 1988-12-14 EP disclosed
EP-0187297-A2 Alkoxy methyl ether and alkoxy methyl ester derivatives SYNTEX (U.S.A.) INC. (US) 1986-07-16 EP disclosed
US-3988446-A Glycerides with anti-inflammatory properties ABBOTT LABORATORIES (US) 1976-10-26 US disclosed