SCHEMBL25751090

SCHEMBL25751090

Cc1ccc(Oc2ccc(-c3ccc(Oc4ccc(N5C(=O)c6ccc(-c7ccc8c(c7)C(=O)N(C)C8=O)cc6C5=O)cc4)cc3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
ALDH1A1 P00352 4/20 0.51
NPC1 O15118 1/20 0.51
TSHR P16473 1/20 0.51
CASP1 P29466 1/20 0.51
RAB9A P51151 1/20 0.51
CASP7 P55210 1/20 0.51
HSD17B10 Q99714 1/20 0.51
BRD4 O60885 1/20 0.48
CA9 Q16790 3/20 0.47
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
ESR1 P03372 1/20 0.47
NPSR1 Q6W5P4 2/20 0.46
MAPT P10636 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA2 P00918 1/20 0.46
POLB P06746 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13018340 1.00 MEN1 (0.53) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL13018338 1.00 MEN1 (0.53) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL13018341 1.00 MEN1 (0.53) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL7594849 0.99 MEN1 (0.54) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL757748 0.93 MEN1 (0.61) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL12317361 0.92 BRD4 (0.60) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL13018339 0.92 CA9 (0.51) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL13018342 0.92 ALDH1A1 (0.59) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL13533870 0.92 ALDH1A1 (0.59) MEN1KMT2AALDH1A1NPC1TSHR
SCHEMBL10053199 0.90 CA9 (0.52) MEN1KMT2AALDH1A1NPC1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230205031-A1 ELECTROCHROMIC COMPOSITION, ELECTROCHROMIC LAYER AND ELECTROCHROMIC DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-29 US disclosed