Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15359996 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL12435747 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL7594332 | 0.80 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL713051 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL7573848 | 0.78 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL7571186 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KDM4ENPC1TSHRSMN1; SMN2 | |
| SCHEMBL13011714 | 0.78 | KMT2A (0.74) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL18152540 | 0.77 | BCL2A1 (0.81) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9931015 | 0.77 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AMAPTUSP2 | |
| SCHEMBL1417269 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |