Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6232649 | 0.99 | PNMT (0.41) | PNMTNPC1RAB9ASIGMAR1HTR7 | |
| Hydrochloric Acid SCHEMBL7579430 | 0.90 | PNMT (0.43) | PNMTNPC1RAB9ASIGMAR1HTR7 | |
| Hydrochloric Acid SCHEMBL7580952 | 0.86 | PNMT (0.40) | PNMTNPC1RAB9ASIGMAR1HTR7 | |
| Hydrochloric Acid SCHEMBL5079549 | 0.86 | PNMT (0.34) | PNMTNPC1RAB9ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL7641528 | 0.84 | PNMT (0.45) | PNMTNPC1RAB9ASIGMAR1HTR7 | |
| Hydrochloric Acid SCHEMBL7580056 | 0.81 | PNMT (0.38) | PNMTNPC1RAB9ASIGMAR1HTR7 | |
| Hydrochloric Acid SCHEMBL7577060 | 0.81 | PNMT (0.38) | PNMTNPC1RAB9ASIGMAR1HTR7 | |
| SCHEMBL797346 | 0.81 | PNMT (0.40) | PNMTNPC1RAB9ASIGMAR1HTR7 | |
| Hydrochloric Acid SCHEMBL5079479 | 0.77 | PNMT (0.35) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL7639886 | 0.77 | PNMT (0.46) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729968-B1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2002-09-25 | — | — | EP | claimed |