SCHEMBL757841

SCHEMBL757841

NC(C(=O)O)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3798816 1.00
SCHEMBL29057555 0.81 SLC7A5 (0.46)
SCHEMBL29032593 0.81 SLC7A5 (0.46)
SCHEMBL3797378 0.79 USP2 (0.50)
SCHEMBL3797376 0.79 USP2 (0.50)
SCHEMBL23200783 0.79 USP2 (0.50)
SCHEMBL4957561 0.79 USP2 (0.50)
SCHEMBL600021 0.78 SLC7A5 (0.62)
SCHEMBL1007447 0.78 SLC7A5 (0.62)
SCHEMBL468084 0.78 SLC7A5 (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116365044-A Electrolyte, secondary battery and electric equipment 欣旺达电动汽车电池有限公司 2023-06-30 CN claimed
CN-116365044-A Electrolyte, secondary battery and electric equipment 欣旺达电动汽车电池有限公司 2023-06-30 CN disclosed
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF RAYZEBIO, INC. 2023-05-25 US disclosed
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF RAYZEBIO, INC. 2023-05-25 US disclosed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
US-10851119-B2 Boron-containing diacylhydrazines INTREXON CORPORATION (US) 2020-12-01 US disclosed
US-20200157122-A1 BORON-CONTAINING DIACYLHYDRAZINES INTREXON CORP (US) 2020-05-21 US disclosed
CN-107406373-B Boron-containing diacylhydrazine compounds 英特瑞克斯顿股份有限公司 2020-04-28 CN disclosed
EP-3194359-B1 BORON-CONTAINING DIACYLHYDRAZINE COMPOUNDS INTREXON CORP (US) 2020-04-08 EP disclosed
US-10570158-B2 Boron-containing diacylhydrazine compounds INTREXON CORPORATION (US) 2020-02-25 US disclosed
EP-1076563-A4 DIPEPTIDE CASPASE INHIBITORS AND THE USE THEREOF CYTOVIA INC (US) 2003-04-23 EP disclosed
EP-0822827-B1 ANTAGONISTS OF LHRH UNIV TEXAS (US) 2003-03-05 EP disclosed
EP-1076563-A1 DIPEPTIDE CASPASE INHIBITORS AND THE USE THEREOF Cytovia, Inc. (US) 2001-02-21 EP disclosed
US-6153591-A PROTECTING NERVOUS SYSTEM FOLLOWING FOCAL ISCHEMIA AND GLOBAL ISCHEMIA; ALZHEIMER'S DISEASE, HUNTINGTON'S DISEASE, PRION DISEASES, PARKINSON'S DISEASE, MULTIPLE SCLEROSIS, AMYOTROPHIC LATERAL SCLEROSIS, ALOPACIA, RHEUMATOID ARTHRITIS CYTOVIA, INC. (US) 2000-11-28 US disclosed
WO-1999047154-A1 DIPEPTIDE CASPASE INHIBITORS AND THE USE THEREOF CYTOVIA, INC. (US) 1999-09-23 WO disclosed
US-5632991-A ADMINISTERING AN IMMUNOCONJUGATE OF MONOCLONAL ANTIBODY H18/7 AND A DRUG; ANTICOAGULANTS;-INFLAMMATORY AND -TUMOR AGENTS; COMPLEMENT INHIBITORS; IMMUNOSUPPRESSANTS BRIGHAM & WOMEN'S HOSPITAL (US) 1997-05-27 US disclosed
EP-0534944-B1 ANTIBODIES SPECIFIC FOR ELAM-1 AND THE USE THEREOF BRIGHAM & WOMENS HOSPITAL (US) 1996-09-11 EP disclosed
EP-0595794-B1 CLONED GENES WHICH ENCODE ELAM-1 AND FUSION PROTEINS THEREOF, THE PROTEIN PRODUCTS EXPRESSED THEREFROM, PHARMACEUTICAL COMPOSITIONS AND THE USE THEREOF BRIGHAM & WOMENS HOSPITAL (US) 1996-08-14 EP disclosed
US-5403713-A Administering detectable amount of labeled anti-elam-1 monoclonal antibody and detecting the label BRIGHAM & WOMEN'S HOSPITAL (US) 1995-04-04 US disclosed
US-5081034-A CLONED GENES WHICH ENCODE ELAM-1 BRIGHAM & WOMEN'S HOSPITAL (US) 1992-01-14 US disclosed