Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | RRM1 | P23921 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21399748 | 0.88 | SIRT6 (0.36) | GABRR1DPP7 | |
| SCHEMBL26731701 | 0.87 | GABRR1 (0.41) | GABRR1GABBR2GABBR1DPP7RRM1 | |
| SCHEMBL19605496 | 0.86 | SIRT6 (0.42) | — | |
| SCHEMBL13233703 | 0.86 | SIRT6 (0.42) | — | |
| SCHEMBL21166946 | 0.85 | GABRR1 (0.40) | GABRR1GABBR2GABBR1DPP7 | |
| SCHEMBL12762368 | 0.85 | GABRR1 (0.40) | GABRR1GABBR2GABBR1DPP7 | |
| SCHEMBL8191952 | 0.83 | GABRR1 (0.52) | GABRR1GABBR2GABBR1 | |
| SCHEMBL756912 | 0.83 | GABRR1 (0.52) | GABRR1GABBR2GABBR1 | |
| SCHEMBL21166859 | 0.80 | CA1 (0.34) | — | |
| SCHEMBL10206348 | 0.80 | HDAC7 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138361-B2 | C-10 carbamates of taxanes | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-03-20 | — | — | US | disclosed |