Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | RORA | P35398 | 1/20 | 0.62 |
| ▸ | RORC | P51449 | 1/20 | 0.62 |
| ▸ | RORB | Q92753 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | BRAF | P15056 | 1/20 | 0.57 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29031229 | 0.91 | MEN1 (0.77) | MEN1KMT2ASMN1; SMN2HTTRORA | |
| SCHEMBL4709087 | 0.84 | MEN1 (0.84) | MEN1KMT2ASMN1; SMN2HTTHPGD | |
| SCHEMBL10192087 | 0.83 | HTT (0.88) | MEN1KMT2ASMN1; SMN2HTTRORA | |
| SCHEMBL7569646 | 0.83 | MEN1 (0.71) | MEN1KMT2ASMN1; SMN2HTTRORA | |
| SCHEMBL12334082 | 0.83 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2HTTRORA | |
| SCHEMBL29118873 | 0.83 | MEN1 (0.71) | MEN1KMT2ASMN1; SMN2HTTRORA | |
| SCHEMBL8266867 | 0.82 | MEN1 (0.66) | MEN1KMT2ASMN1; SMN2HTTRORA | |
| SCHEMBL12334083 | 0.80 | MEN1 (1.00) | MEN1KMT2ASMN1; SMN2HTTRORA | |
| SCHEMBL18109239 | 0.79 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2HTTRORA | |
| SCHEMBL7946591 | 0.79 | HPGD (0.68) | MEN1KMT2ASMN1; SMN2HTTRORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |