Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | RORA | P35398 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.55 |
| ▸ | RORB | Q92753 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29031229 | 0.87 | MEN1 (0.77) | HPGDPKMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29118873 | 0.82 | MEN1 (0.71) | HPGDPKMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20245200 | 0.82 | LMNA (0.84) | HPGDPKMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4709087 | 0.80 | MEN1 (0.84) | HPGDPKMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7578748 | 0.79 | MEN1 (0.67) | HPGDPKMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12334082 | 0.79 | MEN1 (0.67) | HPGDPKMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7569646 | 0.79 | MEN1 (0.71) | HPGDPKMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10192087 | 0.79 | HTT (0.88) | HPGDPKMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2691075 | 0.79 | HPGD (0.64) | HPGDPKMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8290513 | 0.78 | MEN1 (0.65) | HPGDPKMLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262084-B1 | Compounds that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION | 2001-07-17 | — | — | US | disclosed |