Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | MEN1 | O00255 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23200286 | 0.91 | MEN1 (0.67) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL29834290 | 0.90 | LMNA (0.68) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL30257110 | 0.90 | LMNA (0.68) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL23200348 | 0.90 | LMNA (0.68) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL23200273 | 0.90 | LMNA (0.68) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL20560509 | 0.87 | KMT2A (0.62) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL23200266 | 0.85 | KDM4E (0.73) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL23200304 | 0.85 | KMT2A (0.67) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL23200361 | 0.84 | MEN1 (0.62) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL7572268 | 0.84 | KDM4E (0.69) | KMT2AMEN1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |