Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.60 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL760141 | 0.88 | PDE4B (0.56) | HSD17B2MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL2124837 | 0.87 | MAPK1 (0.58) | HSD17B2MEN1KMT2ARAB9APOLB | |
| SCHEMBL155638 | 0.84 | HSD17B2 (1.00) | HSD17B2MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL13074870 | 0.83 | CA12 (0.69) | HSD17B2MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL16068652 | 0.83 | HSD17B2 (0.50) | HSD17B2MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL16068855 | 0.83 | HSD17B2 (0.50) | HSD17B2MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL15289000 | 0.83 | MEN1 (1.00) | HSD17B2MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL29532454 | 0.83 | MEN1 (1.00) | HSD17B2MEN1KMT2ARAB9AKDM4E | |
| Alcohol SCHEMBL27898607 | 0.81 | HSD17B2 (0.94) | HSD17B2MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL3278089 | 0.81 | MEN1 (0.74) | HSD17B2MEN1KMT2ARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217093-B1 | FLAVOUR-MODULATING COMPOUNDS | GIVAUDAN SA (CH) | 2012-03-21 | — | — | EP | claimed |
| EP-2217093-A1 | FLAVOUR-MODULATING COMPOUNDS | Givaudan SA (CH) | 2010-08-18 | — | — | EP | claimed |
| WO-2009055953-A1 | FLAVOUR-MODULATING COMPOUNDS | GIVAUDAN SA (CH) | 2009-05-07 | — | — | WO | claimed |
| EP-2217093-B1 | FLAVOUR-MODULATING COMPOUNDS | GIVAUDAN SA (CH) | 2012-03-21 | — | — | EP | disclosed |
| EP-2217093-B1 | FLAVOUR-MODULATING COMPOUNDS | GIVAUDAN SA (CH) | 2012-03-21 | — | — | EP | disclosed |
| WO-2009055953-A1 | FLAVOUR-MODULATING COMPOUNDS | GIVAUDAN SA (CH) | 2009-05-07 | — | — | WO | disclosed |
| US-5070087-A | Aryl(alkyland alkylene)-N-((phenoxy and phenylthio)alkyl) aminoheterocyclics as cardiovascular, anthihistaminic, antisecretory and antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |