Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.56 |
| ▸ | PDE4A | P27815 | 3/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL757997 | 0.88 | HSD17B2 (0.72) | HSD17B2MEN1RAB9AKMT2ACA12 | |
| SCHEMBL2124837 | 0.87 | MAPK1 (0.58) | HSD17B2MEN1RAB9AKMT2ACA12 | |
| SCHEMBL460455 | 0.84 | HSD17B2 (0.77) | PDE4BPDE4APDE4CPDE4DHSD17B2 | |
| SCHEMBL13074870 | 0.83 | CA12 (0.69) | HSD17B2MEN1RAB9AKMT2ACA12 | |
| SCHEMBL17420540 | 0.83 | TAS1R3 (0.52) | HSD17B2MEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL30628203 | 0.83 | TAS1R3 (0.52) | HSD17B2MEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL10044243 | 0.81 | HSD17B2 (0.52) | PDE4BPDE4APDE4CPDE4DHSD17B2 | |
| SCHEMBL16068652 | 0.80 | HSD17B2 (0.50) | HSD17B2MEN1RAB9AKMT2AKDM4E | |
| SCHEMBL16068855 | 0.80 | HSD17B2 (0.50) | HSD17B2MEN1RAB9AKMT2AKDM4E | |
| SCHEMBL10422057 | 0.79 | HSD17B2 (0.64) | PDE4BPDE4APDE4CPDE4DHSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217093-B1 | FLAVOUR-MODULATING COMPOUNDS | GIVAUDAN SA (CH) | 2012-03-21 | — | — | EP | claimed |
| EP-2217093-A1 | FLAVOUR-MODULATING COMPOUNDS | Givaudan SA (CH) | 2010-08-18 | — | — | EP | claimed |
| WO-2009055953-A1 | FLAVOUR-MODULATING COMPOUNDS | GIVAUDAN SA (CH) | 2009-05-07 | — | — | WO | claimed |
| EP-2217093-B1 | FLAVOUR-MODULATING COMPOUNDS | GIVAUDAN SA (CH) | 2012-03-21 | — | — | EP | disclosed |
| EP-2217093-A1 | FLAVOUR-MODULATING COMPOUNDS | Givaudan SA (CH) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009055953-A1 | FLAVOUR-MODULATING COMPOUNDS | GIVAUDAN SA (CH) | 2009-05-07 | — | — | WO | disclosed |
| WO-2009055953-A1 | FLAVOUR-MODULATING COMPOUNDS | GIVAUDAN SA (CH) | 2009-05-07 | — | — | WO | disclosed |