⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1324583 | 0.74 | — | — | |
| SCHEMBL8548893 | 0.69 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL11941670 | 0.67 | — | — | |
| SCHEMBL22960999 | 0.66 | — | — | |
| SCHEMBL337151 | 0.65 | TSHR (0.33) | — | |
| SCHEMBL28960387 | 0.64 | ALDH1A1 (0.33) | — | |
| SCHEMBL22386696 | 0.64 | — | — | |
| SCHEMBL1324048 | 0.64 | POLB (0.42) | — | |
| SCHEMBL231128 | 0.64 | — | — | |
| SCHEMBL28774228 | 0.63 | ATM (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780548-A | POLYESTER BLEND; CONTAINS THE RESIDUE OF A MALEIC ACID ESTER, MALEIMIDE, MALEINAMIC ACID ESTER, AN OXAZOLINE, OXAZINE, OXAZOLONE, OR OXAZINONE | GENERAL ELECTRIC COMPANY (US) | 1998-07-14 | — | — | US | claimed |
| EP-0771850-B1 | Polyphenylene ether resin composition | GEN ELECTRIC (US) | 2002-10-09 | — | — | EP | disclosed |
| US-5780548-A | POLYESTER BLEND; CONTAINS THE RESIDUE OF A MALEIC ACID ESTER, MALEIMIDE, MALEINAMIC ACID ESTER, AN OXAZOLINE, OXAZINE, OXAZOLONE, OR OXAZINONE | GENERAL ELECTRIC COMPANY (US) | 1998-07-14 | — | — | US | disclosed |
| EP-0771850-A1 | Polyphenylene ether resin composition | GENERAL ELECTRIC COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |