Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7577057 | 1.00 | PNMT (0.37) | PNMTNPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL7580948 | 0.95 | PNMT (0.38) | PNMTNPC1RAB9ASIGMAR1 | |
| SCHEMBL7197599 | 0.84 | PNMT (0.39) | PNMTNPC1RAB9ASIGMAR1 | |
| SCHEMBL7579424 | 0.81 | PNMT (0.41) | PNMTNPC1RAB9AALDH1A1 | |
| SCHEMBL7641521 | 0.79 | PNMT (0.44) | PNMTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL5351418 | 0.79 | PNMT (0.42) | PNMTNPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL797346 | 0.74 | PNMT (0.40) | PNMTNPC1RAB9ASIGMAR1 | |
| SCHEMBL5854187 | 0.74 | GAA (0.42) | NPC1RAB9ALMNAGAA | |
| SCHEMBL5854675 | 0.74 | GAA (0.42) | NPC1RAB9ALMNAGAA | |
| Hexane SCHEMBL8572947 | 0.74 | PNMT (0.47) | PNMTNPC1RAB9AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729968-B1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2002-09-25 | — | — | EP | disclosed |
| US-6365764-B1 | METALLOCENE COMPOUNDS HAVING TWO FLUORENYL LIGANDS BRIDGED WITH A SINGLE SILICON OR GERMANIUM ATOM | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-04-02 | — | — | US | disclosed |
| US-6180733-B1 | OLEFIN POLYMERIZATION USING CATALYST COMPRISING THE PRODUCT OF REACTION BETWEEN A GROUP 4 OR 5 METALLOCENE COMPOUND AND AN ALUMOXANE, OPTIONALLY WITH ORGANOALUMINUM OR COMPOUND ABLE TO GIVE A METALLOCENE ALKYL CATION; ATACTIC POLYPROPYLENE | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-01-30 | — | — | US | disclosed |
| US-6054404-A | COORDINATION CATALYST | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-04-25 | — | — | US | disclosed |
| US-5786495-A | HIGH MOLECULAR WEIGHT ATACTIC POLYPROPYLENE POLYMERIZATION CATALYST | MONTELL TECHNOLOGY COMPANY BV (NL) | 1998-07-28 | — | — | US | disclosed |
| EP-0729968-A1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | Montell Technology Company bv (NL) | 1996-09-04 | — | — | EP | disclosed |