Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 4/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595832 | 0.98 | MAPK14 (0.40) | MAPK13MAPK12MAPK11MAPK14CYP3A4 | |
| SCHEMBL7575679 | 0.98 | MAPK14 (0.40) | MAPK13MAPK12MAPK11MAPK14CYP3A4 | |
| SCHEMBL7573659 | 0.83 | GCGR (0.40) | CYP3A4CYP2D6GSK3BCLK4LMNA | |
| SCHEMBL7572122 | 0.81 | GCGR (0.41) | CYP3A4CYP2D6GSK3BCLK4LMNA | |
| SCHEMBL7597744 | 0.81 | GCGR (0.41) | CYP3A4CYP2D6GSK3BCLK4LMNA | |
| SCHEMBL7530621 | 0.80 | KCNH2 (0.38) | CYP3A4MAPTTSHR | |
| SCHEMBL7580690 | 0.80 | KCNH2 (0.38) | CYP3A4MAPTTSHR | |
| SCHEMBL7056015 | 0.80 | KCNH2 (0.38) | CYP3A4MAPTTSHR | |
| SCHEMBL7717379 | 0.79 | KCNH2 (0.37) | CYP3A4MAPTTSHR | |
| SCHEMBL7572175 | 0.79 | KCNH2 (0.35) | CYP3A4LMNASMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002096913-A1 | SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES | GENTIAN AS (NO) | 2002-12-05 | — | — | WO | disclosed |