Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056015 | 0.98 | KCNH2 (0.38) | KCNH2HTTTYRMEN1CYP3A4 | |
| SCHEMBL7530621 | 0.98 | KCNH2 (0.38) | KCNH2HTTTYRMEN1CYP3A4 | |
| SCHEMBL7580690 | 0.98 | KCNH2 (0.38) | KCNH2HTTTYRMEN1CYP3A4 | |
| SCHEMBL7717379 | 0.97 | KCNH2 (0.37) | KCNH2HTTTYRMEN1CYP3A4 | |
| SCHEMBL8923586 | 0.88 | S1PR1 (0.44) | MEN1TSHRKMT2AALOX15TDP1 | |
| SCHEMBL4522301 | 0.86 | SPHK2 (0.33) | HTTTYRMEN1CYP3A4TSHR | |
| SCHEMBL7533536 | 0.83 | LIPG (0.34) | KCNH2CYP3A4TSHRMAPTTLR8 | |
| SCHEMBL10595842 | 0.81 | CYSLTR2 (0.44) | MEN1KMT2ATLR8 | |
| SCHEMBL7595832 | 0.81 | MAPK14 (0.40) | CYP3A4TSHRMAPTLMNAHSD17B10 | |
| SCHEMBL7580698 | 0.79 | MAPK13 (0.39) | CYP3A4TSHRMAPTLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002096913-A1 | SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES | GENTIAN AS (NO) | 2002-12-05 | — | — | WO | disclosed |